Find patient medical information for Buspar Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Buspirone may come in a tablet that can be split to get the correct dose for you. Follow the manufacturer's Patient Instruction Sheet or ask your pharmacist how to split the tablet to get your dose.
Do not start, stop, or change the dosage of any medicines without your doctor's approval. Drug interactions may change how your medications work or increase your risk for serious side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.
Buspirone, sold under the brand name Buspar, is an anxiolytic drug that is primarily used to treat generalized anxiety disorder (GAD). It is also commonly used to augment antidepressants in the treatment of major depressive disorder. Unlike most anxiolytics, the pharmacology of buspirone is not related to that of.
There is evidence that buspirone may be used to treat Cerebellar ataxia.
Structural analogues of buspirone include other azapirones like gepirone, ipsapirone, perospirone, and tandospirone.
Buspirone is the INN, BAN, DCF, and DCIT of buspirone, while buspirone hydrochloride is its USAN, BANM, and JAN.
A major metabolite of buspirone, 1-(2-pyrimidinyl)piperazine (1-PP), occurs at higher circulating levels than buspirone itself, and is known to act as a potent α 2 -adrenergic receptor antagonist. However, buspirone has been reported to have shown "significant and selective intrinsic efficacy" at the α 1 -adrenergic receptor expressed in a "tissue- and species-dependent manner".
Mean daily doses at the end of the study were 1.9 mg alprazolam and 18.7 mg buspirone. As judged by the Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, Physician's Global Improvement Scale, and other efficacy scales, alprazolam and buspirone were similar in efficacy, but more effective than placebo.
Mean daily doses at the end of the study were 1.9 mg alprazolam and 18.7 mg buspirone. Significantly more buspirone-treated than alprazolam-treated patients failed to complete the study, primarily because of side effects or inefficacy. No clinically important differences were noted between alprazolam and buspirone in side effects, vital signs, or laboratory test results. As judged by the Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, Physician's Global Improvement Scale, and other efficacy scales, alprazolam and buspirone were similar in efficacy, but more effective than placebo, for treating anxiety and depression symptoms in these patients. Clinically important differences were noted between drugs in the onset of effect, with alprazolam producing rapid and sustained improvement within the first week of treatment and buspirone producing more gradual, continuous improvement throughout the study. The efficacy and safety of alprazolam and buspirone for treating generalized anxiety disorder (GAD) were compared in a 6-week, double-blind, randomized, placebo-controlled study of 94 outpatients. Alprazolam-treated patients most frequently reported central nervous system-related side effects (drowsiness and sedation), while buspirone-treated patients most frequently reported gastrointestinal system-related side effects (appetite disturbances and abdominal complaints).
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Buspar is in fact very old, that is by drug life. It has no better record than benzodiazepines like Diazepam. Again people have a lousy experience with them , anyone I have know to be on Buspar soon got off it quickly because it had little impact. Best to stay free of yet another chemical which in the long term.
Return to Anxiety and Panic Attacks.
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by purplemonkey » Fri Jul 21, 2006 7:33 pm.
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by johnjoe » Tue Aug 01, 2006 6:55 am.
by arkane » Tue Aug 01, 2006 4:27 am.
Buspar is not an "as needed " medication at all. It has to be taken consistently for weeks to get its full effect . I take Buspar and am rather happy with it. Is it as effective as Xanax ? Probably not. The main benefit of Buspar over Xanax is that Buspar has no addiction potential like Xanax. Stopping Buspar will.
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